The SharePoint Server 2007 Scalability and Performance whitepaper. This 90+ page whitepaper documents the architectural design considerations and performance characteristics of a real-world, large-scale SharePoint lab implementation containing around 50 million content items, and reflects both “scale-up” and “scale-out” scenarios.
In adddition to the project that resulted in the Scalability and Performance whitepaper, the KnowledgeLake folks and the author were recently involved in another very challenging proof-of-concept for a large pharmaceutical company, which represented a large-scale SharePoint implementation containing 40 TB of content (about 75 million content items) spread across two SharePoint farms.